Over 1600 Custom NGS Panels (Next-Generation Sequencing Assays) including both DNA and RNA panels have been expertly designed and shipped to hundreds of NGS labs globally for research and testing applications ranging from tumor profiling, cancer liquid biopsy, pharmacogenomics, neurology, cardiology, infectious disease to food safety and agrigenomics.

SPEED. 

Get your custom NGS panel or sequencing panel in 4 weeks

Easily build a CleanPlex Custom NGS or Sequencing Panel to accelerate your research and assay development. Multiplex up to 20,000+ amplicons in each reaction and take advantage of CleanPlex Technology’s high sensitivity, rapid single-tube workflow, and cost-effective sequencing.

Use ParagonDesigner, our free online multiplex PCR primer design tool, to submit your target regions of interest and instantly receive a design coverage report to review. Once you approve the design, your custom NGS amplicon panel will be ready for shipment in 4 weeks.

» Start designing now and obtain a quote 

PERFORMANCE.

Build better and smarter NGS assays

CleanPlex® Custom NGS Amplicon Panels are powered by Paragon Genomics’ CleanPlex NGS Amplicon Sequencing Technology – an ultra-high multiplex PCR-based target enrichment technology for next-generation sequencing (NGS). It features a highly advanced proprietary primer design algorithm and an innovative, patented background cleaning chemistry. Together, they allow CleanPlex Custom NGS Amplicon Panels to break the limits of existing target enrichment technologies (Read this blog article about how). 

» View applications and customer testimonials

CUSTOMIZATION. 

Enjoy the highest level of personalization

Our expert scientists are ready to design and optimize CleanPlex Custom NGS Panels to meet your desired specifications. CleanPlex Custom NGS Panels are designed using Paragon Genomics’ proprietary ParagonDesigner™ algorithm and iteratively optimized in-silico to ensure success of your NGS-based assays. Amplicon size can tailored for your sample types according to your specified input DNA fragment size to generate the highest level of performance.


» View custom NGS panel specifications

PRE-DESIGNED CONTENT. 

Build your NGS sequencing panel faster on top of Paragon curated gene content

To speed up your custom NGS assay development, our team has consulted with leading experts and curated relevant gene content for specific applications such as cardiac diseases and neurodegenerative diseases. These pre-designed NGS panels have already been evaluated in silico and can be made to order fast. You have the option to add new content or modify the existing content of these panels. 


» Learn More …

Animals

Bear

Bear, Brown

UrsArc2.0

Cattle

Cattle

UMD3.1

Chicken

Chicken

GRCg6a

Dog

Dog

canFam3

Dog

Dog

canFam6

Gecko

Gecko

GCF_001447785.1

Hamster

Hamster, Chinese

GCF_001447785.1

Horse

Horse

equCab2

Human

Human

hg19

Human

Human

hg38

Human bisulfite

Human bisulfite converted both strands

hg38_bs

Monkey

Monkey

macFas5

Monkey

Monkey

rheMac2

Mosquito

Mosquito

AgamP4

Mosquito, Malaria

Mosquito, Malaria

AfunF3

Moth

Moth

csiro.29053v1

Mouse

Mouse

mm10

Mouse

Mouse

mm39

Mouse

Mouse

mm39_allContigs

Oyster

Oyster

Oyster

Pig

Pig

Sscrofa11.1

Rat

Rat

Rnor_6.0

Salmon

Salmon, Atlantic

ICSASG_v2

Sheep

Sheep

Oar_v4.0

Whipworm

Whipworm

PRJEB535

Zebrafish

Zebrafish

danRer11

Plant

Cabbage, Chinese

Cabbage, Chinese

Brapa_v1.5

Corn

Corn

AGPv3.22

Corn

Corn

B73

Cotton

Cotton

AD1-NBI_v1.1

Cotton

Cotton

TM1_HAU_v1.0

Eudicot

Eudicot

PhaVulg1

Hemp

Hemp

canSat3

Hemp

Hemp

KNU-18-1

Melon

Melon

CM1.0

Melon

Melon

CM3.6.1

Oilseed rape

Oilseed rape

AST_PRJEB5043_v1

Oilseed rape

Oilseed rape

Darmor_v81

Rice

Rice

IRGSP-1.0

Soybean

Soybean

Gmax.275

Soybean

Soybean

Wm82.a2.v1

Sunflower

Sunflower

HanXRQr1.0

Tomato

Tomato

SL3.00

Tomato

Tomato

SL4.0

Watermelon

Watermelon

97103_v2

Wheat

Wheat

IWGSC_CS_RefSeq_v2.1

Disease

HIV

HIV

HXB2

Malaria parasite

Malaria parasite

Pfalciparum3D7

SARS-CoV-2

SARS-CoV-2

NC_045512.2

TB

TB

H37Rv

Why Choose CleanPlex Custom NGS Sequencing Panels?

Design Custom NGS Assays Online with ParagonDesigner

Get your answers sooner! Using the ParagonDesigner online portal to create a new CleanPlex Custom NGS Panel is quick and easy. Just follow 3 simple steps and our intuitive user interface will guide you through the process. Our design experts will be available to answer your questions, implement additional customization, and provide you a quote.

» Start Designing Now

When we decided to choose a sequencing platform, we had several choices and I am delighted that we chose Paragon Genomics. Paragon Genomics has enabled us to move our sequencing in-house with an affordable and easy-to-use product. They assisted us every step along the way from choosing the amplicons, to guiding us through library preparation to assisting with analysis. I strongly recommend their CleanPlex® amplicon-based targeted sequencing approach and could not be happier with their product.

Elliot Stieglitz, MD, Assistant Professor, University of California San Francisco

Need Functional Validation?

Our expert scientists are here to support you from design to validation for your assay development project. Paragon Genomics provides extensive wet-lab validation and optimization to ensure optimal performance of your custom NGS assay on your specified sample type and quick transition of the assay into your lab.

What’s Included in My CleanPlex Custom NGS Panel?

Each CleanPlex Custom NGS Panel contains all reagents necessary to construct target-enriched, sequencing-ready NGS amplicon libraries from input DNA. Your CleanPlex Custom NGS Panel will include a CleanPlex Targeted Library Kit, your custom multiplex PCR primer mix, CleanMag® Magnetic Beads for bead purification, and Illumina® or Ion Torrent index primers for multiplexing and sequencing on the platform of your choice.

Request a Free Custom Sequencing Panel Design Consultation

Enter your email below to schedule a free consultation with our PhD-level expert scientists to learn how our best-in-class custom NGS panel design services can help you advance your precision medicine testing and research.